Harry Kane scored his 36th goal of the season but Bayern Munich let a second-half lead slip to draw 2-2 with Hamburg SV.
Late goals from Dani Olmo and Robert Lewandowski earned LaLiga leaders Barcelona a hard-fought 2-0 victory over Espanyol.
Liverpool shrugged off the absence of Mohamed Salah as midfielder Dominik Szoboszlai scored an 88th-minute penalty to give them a 1-0 Champions League win at Inter Milan.
IMAGES from the UEFA Champions League matches played on Wednesday.
Barcelona captain Raphinha scored twice as they returned to winning ways in LaLiga for the first time in a month with a 5-1 victory at Mallorca on Tuesday.
IMAGES from soccer matches played across Europe on Sunday.
A round-up of Wednesday's UEFA Champions League last-16 first leg matches.
Roundup of Champions League matches played on Wednesday night
Croatian forward Ante Budimir scored twice to help Osasuna earn a shock 4-2 home win over leaders Barcelona.
Karim Benzema and Vinicius Jr both scored a brace to give the LaLiga leaders a 4-1 home win over Valencia
The player, who has a penchant for making jibes at Real Madrid, also cited remarks made by former referee Eduardo Iturralde Gonzalez, who said last year that 90% of referees were Real fans, the remaining 10% supporting Barca.
Manuel Neuer remained Germany's number one and captain, even as they underperformed in the UEFA Nations League and Euro 2020 qualifiers.
Barcelona's Raphinha scored deep into stoppage time to hand his side a dramatic 5-4 comeback win at Benfica and a place in the Champions League last 16.
IMAGES from football matches played across leagues in Europe on Sunday.
IMAGES from the Champions League quarter-final played between Barcelona and Bayern Munich in Lisbon on Friday.
IMAGES from the Champions League matches played on Tuesday.
Images from Saturday's action in La Liga.
IMAGES from the La Liga matches played on Tuesday
Treble-chasing Barcelona are exactly where they want to be as they prepare for two matches this week that could make or break coach Luis Enrique's first season in charge.
Here is how some Barca and Bayern players reacted to the result.
Manchester City squandered a three-goal lead to draw 3-3 with Feyenoord in the Champions League on Tuesday.
Unzue is one of the two leading candidates to succeed Luis Enrique, who announced this month he will leave at the end of this season, along with Athletic Bilbao coach Ernesto Valverde.
La Liga champions Barcelona fell to their first opening day defeat of the season in 11 years when they were beaten 1-0 at Athletic Bilbao thanks to a sensational late overhead kick from veteran striker Aritz Aduriz.
Lionel Messi completed a sparkling performance by chipping the goalkeeper from the edge of the area as Barcelona swept aside ten-man Levante 5-0 away on Sunday to continue their winning start at the top of La Liga.
Neuer sidelined for 'coming weeks' after knee surgery - Bayern
Tuesday's match was the latest masterclass from the South American trio, known in Spain as 'MSN', whose goals have put Barca on the brink of repeating 2009's treble of Champions League and Spanish league and Cup triumphs, the only time a La Liga club have achieved the feat.
Neto will sign a four-year deal with Barcelona that will keep him at the club until the end of the 2022-23 season and he will replace Dutch goalkeeper Jasper Cillessen who moved the other way on Wednesday.
Lionel Messi led Barcelona to a 3-1 win at home to Napoli for a 4-2 aggregate victory which took the club into the Champions League quarter-finals, where they face Bayern Munich.
Confusing an FC Copenhagen player into believing he was offside when clear through on goal earned Barcelona's Jose Manuel Pinto a two-match Champions League ban from UEFA on Friday.
Sweden striker Zlatan Ibrahimovic made his debut for Barcelona in the second half of their 1-0 defeat by Manchester City in the Joan Gamper Trophy on Wednesday.
Barcelona's poor run away to Real Sociedad continued when the champions were held to a 1-1 draw at Anoeta on Sunday and slipped six points behind La Liga leaders Real Madrid before next week's 'Clasico' against their arch rivals.
Images from the soccer matches played across Europe on Saturday.
Gareth Bale raced away to score a stunning late winner as Real Madrid made light of the absence of top scorer Cristiano Ronaldo to beat arch-rivals Barcelona 2-1 to win a riveting King's Cup final on Wednesday.
Leicester City's Kelechi Iheanacho scored two poacher's goals as they beat Manchester United 3-1 in their FA Cup quarter-final on Sunday to set up a last-four clash against Southampton.
Cristiano Ronaldo crushed Barcelona's treble hopes with two goals in a 3-1 away win for Real Madrid in their King's Cup last four, second leg on Tuesday to set up a showdown against Atletico Madrid or Sevilla in May's final.
It was Messi's 56th converted penalty in La Liga and saw him draw level with Hugo Sanchez as the league's second-top penalty taker, behind record holder Cristiano Ronaldo on 61.
Real Madrid's unbeaten start to the La Liga season came to an abrupt and surprising end as Real Mallorca claimed a stunning 1-0 victory at a rocking Son Moix on Saturday to climb out of the relegation zone.
Luis Suarez had the Barcelona fans chanting his name after he set up Lionel Messi to score the opening goal in their King's Cup semis.
Bayern Munich thrashed Bayer Leverkusen 5-1, while Barcelona came from behind to beat Valencia 3-1 in LaLiga at Camp Nou on Sunday.
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